The prevalence of lupus anticoagulant in normal pregnancy and in women with recurrent fetal loss—recommendations for laboratory testing for lupus anticoagulant
نویسندگان
چکیده
منابع مشابه
Lupus anticoagulant and recurrent fetal loss: successful treatment with gammaglobulin.
SIR,-Dr Martyn and colleagues (June 11, p 1319) suggest that motoneuron disease (MND) is a rare and delayed consequence of an infection with poliovirus. The role of poliovirus in the aetiology of MND remains equivocal’ because of the problems associated with prospective case-control studies and lack of laboratory proof of poliovirus infection in cases of MND. Poliomyelitis is very common in Ind...
متن کاملLupus anticoagulant (LA) in pregnant women with history of recurrent fetal loss
The frequency of LA in 50 women with intact pregnancy, age range 26 to 39 years, but with past history of at least 2 lost pregnancies, was determined using coagulation-based assays. Most (68%) of the pregnant women were in the first trimester. Venous blood (4.5 mL) carefully collected from each of the subjects and also the controls (normal relative donors) was put in 0.5 mL of 3.8% citrate (rat...
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This issue of Clinical Chemistry and Laboratory Medicine includes a report by Pradella and colleagues regarding a cooperative multicentre study to define the upper limits of normal for several tests used in the diagnostic assessment of lupus anticoagulant (LA) [1] . In total, 200 normal samples were assessed, comprising 40 from each of five centres, for a total of six functional LA assays. Each...
متن کاملLupus anticoagulant, anticardiolipin antibodies, fetal loss, and systemic lupus erythematosus.
UPUS ANTICOAGULANTS (LA) and anticardioL lipin (ACL) antibodies (ACLA) belong to a heterogenous group of antibodies directed against negatively charged pho~pholipids.l-~ However, more recent studies would suggest that these antibodies are directed to epitopes of other proteins that are complexed with negatively charged phospholipid~>-~ Although antiphospholipid antibodies are frequently found i...
متن کاملIncreased mortality in patients with the lupus anticoagulant: the Vienna Lupus Anticoagulant and Thrombosis Study (LATS).
Data on the clinical course of lupus anticoagulant (LA)-positive individuals with or without thrombotic manifestations or pregnancy complications are limited. To investigate mortality rates and factors that might influence mortality, we conducted a prospective observational study of LA-positive individuals. In total, 151 patients (82% female) were followed for a median of 8.2 years; 30 of the p...
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ژورنال
عنوان ژورنال: Annals of Saudi Medicine
سال: 2004
ISSN: 0256-4947,0975-4466
DOI: 10.5144/0256-4947.2004.429